Webb27 mars 2024 · Although the incidence of isolated ipsilateral local and regional recurrence (IILRR) in human epidermal growth factor 2 (HER2)-negative luminal breast cancer is low, it is important because of its potential risk of distant metastasis and breast cancer related mortality. The aim of this study was to investigate prognostic factor and survival of IILRR … Webb1 jan. 2024 · To address this, our lab uses a transgenic mouse model that recapitulates many of the features of dormancy and recurrence in breast cancer. In this model, doxycycline administration to bitransgenic MMTV-rtTA;TetO-Her2 (MTB/TAN) mice leads to Her2 expression and the formation of invasive mammary adenocarcinomas.
Five natural compounds that help fight HER2 breast cancer
Webb17 nov. 2024 · HER2 is overexpressed and mutated in various types of cancer thus becoming prone to chemotherapy drug resistance. The purpose of this study was to investigate the potential of curcumin,... Webb1 juni 2024 · Consistent with previous studies, higher dose curcumin (18 μmol/L) inhibits Her2-Akt pathway signaling (pHer2, total Her2 and pAkt levels) and cell growth using … humana medicare advantage plan appeal form
Lower concentrations of curcumin inhibit Her2-Akt pathway
Webb27 juli 2024 · 9 October 2024. Berberine has been shown in research to work along a number of quite separate pathways against cancer; it reduces blood sugar levels, it reduces inflammation, boosts immune response and attacks certain pathogens; it blocks Akt and mTOR, while promoting AMPK and weakening the cancer cells, and acts as both a … Webb25 juni 2015 · Amplification of the HER2 gene (also known as neu or ErbB2) or overexpression of HER2 protein has become a solicitous therapeutic target in metastatic … Webb27 juli 2024 · Five natural, bioactive compounds have been shown to improve HER2 treatments while also being active against HER2 positive breast cancer in their own … humana medicare advantage plan hmo