Hif 1 alpha uniprot

Web14 de abr. de 2024 · 1 Introduction. Worldwide, colorectal cancer (CRC) is the third most lethal malignant tumor and the fourth most frequently diagnosed malignant tumor (1, 2).The global incidence and mortality of CRC are increasing because of the continuously expanding and aging of the population with no differences between the sexes ().CRC accounts for … Web10 de abr. de 2024 · Summary. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a …

HIF1A Antibody Affinity Biosciences

WebCrystal structure of a hydroxylated hif-1 alpha peptide bound to the pvhl/elongin-c/elongin-b complex . Experiment type: X-ray diffraction, resolution 2.00Å Release ... This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure. WebUniProt : Q16665; Isotype : Rabbit IgG Clonality : Monoclonal; Price : $185/50μl, $299/100μl Availability : Ship next day Rank: Download datasheet [PDF] : Category. Primary Antibodies; ... HIF-1 alpha Antibody detects endogenous levels of total HIF-1 … software developer cover letter https://tri-countyplgandht.com

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals ...

WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed ... http://www.abways.com/showproduct.asp?cid=CY5197 WebIn HeLa cells, the levels of HIF-1 alpha and HIF-1 beta protein and HIF-1 DNA-binding activity increased exponentially as cellular oxygen tension decreased, with maximum values at 0.5% oxygen and half-maximal values at 1.5 to 2% oxygen. HIF-1 alpha and HIF-1 beta (ARNT) mRNAs were detected in all human, mouse, and rat organs assayed and mRNA ... slow downer music

RCSB PDB - 1H2M: Factor Inhibiting HIF-1 alpha in …

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Hif 1 alpha uniprot

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WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed ... WebProduct Specific Information. MA1-516 detects hypoxia-inducible factor 1 alpha (HIF-1 alpha) from human, non-human primate, bovine, mouse and porcine cells. This antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, immunocytochemistry ...

Hif 1 alpha uniprot

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WebA fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [UniProt# Q61221]. Purification Purified by antigen-affinity chromatography Conjugation … Web22 de out. de 2009 · Factor inhibiting HIF-1 alpha in complex with 8-hydroxyquinoline. Factor inhibiting HIF-1 alpha in complex with 8-hydroxyquinoline. ... 1.14.11.30 …

Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent … Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent …

WebThis kit recognizes Human HIF-1α in samples. No significant cross-reactivity or interference between Human HIF-1α and analogues was observed. Both intra-CV and inter-CV are < 10%. This ELISA kit applies to the in vitro quantitative determination of Human HIF-1α concentrations in serum, plasma and other biological fluids. Web3 de jul. de 2003 · Hypoxia-inducible factor 2-alpha (HIF-2-alpha; HIF2-alpha) Member of PAS protein 2; PAS domain-containing protein 2; Gene names. Name. EPAS1. …

WebHuman HIF-1 alpha ELISA kit (ab275103) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of Human HIF-1 alpha protein in cell and tissue extracts. It uses our proprietary SimpleStep ELISA® technology. Quantitate Human HIF-1 alpha with 33.39 pg/mL sensitivity.

WebCharacterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins. Biochem Biophys Res Commun 260, 557-561. Tanimoto, K., Makino, Y., Pereira, T., and Poellinger, L. (2000). Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein. software developer diversity and inclusionWebAnti-HIF-1 alpha antibody [H1alpha67] (ab1) ... Information by UniProt; ... Immunohistochemical analysis of paraffin-embedded human lung tissue labeling Neurogranin with ab273444 at 1/10000 (0.111 ug/ml) dilution followed by a ready to use LeicaDS9800 (Bond® Polymer Refine Detection) was used. slow down fan on computerWebCell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1α, Arnt 1 (also designated HIF-1β), EPAS-1 (also designated HIF-2α) and HIF-3α, induce glycolysis, erythropoiesis and angiogenesis in … software developer entry level jobs canadaWeb16 de jun. de 2003 · Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the … software developer donovan meyer las vegasWebA fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [UniProt# Q61221]. Purification Purified by antigen-affinity chromatography Conjugation Unconjugated. RRID AB_625919 Note For laboratory use only. Not for any clinical, therapeutic, or ... software developer does whatWebWe investigated the impact of inhibiting HIF-1α transcriptional activity on cytotoxic immune cell infiltration into B16-F10 melanoma. We showed that tumors expressing a deleted form of HIF-1α displayed increased levels of NK and CD8 + effector T cells in the tumor microenvironment, which was associated with high levels of CCL2 and CCL5 ... software developer engineer in test salaryWebImmunocytochemistry analysis of HIF1A in immersion fixed HeLa human cervical epithelial carcinoma cell line treated with DFOA. Samples were incubated in HIF1A monoclonal antibody (Product # MA1-16504) using a dilution of 1 µg/mL followed by donkey anti-rabbit secondary antibody and counterstained with DAPI (blue). software developer engineer apprentice