Cisplatin hela

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WebCisplatin combination drugs induce stronger effects on autophagy than either of the components does. Combination drug-induced autophagy inhibits the growth of HeLa cell in a dose-dependent manner and …

Chemotherapy with cisplatin: insights into intracellular pH and ...

WebResults: HeLa and SiHa cells were more sensitive to cisplatin and oxaliplatin treatment than C33A cells. HeLa and SiHa cells had significantly lower NRF2 gene levels, NQO1 … WebIn vitro response to ionizing radiation (IR), cisplatin (cDDP), hyperthermia (HT) and PARP1-inhibition (PARP1- i) as single and combinational treatments in four cervical cancer cell lines (SiHa, HeLa, CaSki and C33A). ( A) Normalized colony formation after IR in combination with cDDP or ( B) with HT. biofit triple b

Drug: Cisplatin - Cancerrxgene - Genomics of Drug Sensitivity in …

WebWestern Blots showed that cisplatin decreased protein expression of E6 and increased protein expression of P53, p21 and Bax but had no effect on protein expression of … WebFeb 11, 2024 · Subsequently, cells were treated with IC 50 doses of 5-FU (17.58 μM: SiHa; 15.31 μM: HeLa) and cisplatin (24.14 μM: SiHa; 6.82 μM: HeLa) for 48 h and the exosomes were isolated from the conditioned media of treated cells. The exosomal RNA was isolated and examined for modulation of HPV transcripts by type-specific HPVE6 and E7 RT-PCR. WebMay 1, 1996 · The intraperitoneal (i.p.) administration of cisplatin (CDDP) is one of the most effective therapies for cancers that are confined to the abdominal cavity. However, the … biofit walmart

Apoptosis of HeLa cells induced by cisplatin and its …

Roles of SLX1–SLX4, MUS81–EME1, and GEN1 in avoiding genome …

WebApr 11, 2024 · HIGHLIGHTS who: Umit Aliyaskarova from the Universitu00e9 Nazarbayev University have published the paper: NEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells, in the Journal: Scientific … Neil3-mediated proteasomal degradation facilitates the repair of cisplatin-induced dna … WebHeLa Kyoto cells were treated for 1 h with 0.2 μg/mL colcemid 48 h after exposure to cisplatin. Both undamaged and damaged GM08505 cells were treated with colcemid 72 h after the first transfection (where indicated, GM08505 cells were treated with 1 μM cisplatin for 24 h prior to colcemid treatment). daikin air conditioner market shareWebJan 12, 2024 · Cisplatin-resistant HeLa cells were transfected with NHERF1 and overexpression of NHERF1 protein was confirmed by Western blotting ( Figure 2 A). Effect of NHERF1 on cell growth was examined by CCK8 … biofit vertical

"WebMixed lineage leukemia 5 (MLL5) transactivates the expression of E6 and E7 oncogenes in cervical cancer cells. In this study, we utilized CRISPR/Cas9 system with the aim to … " - Cisplatin hela

Cisplatin hela

Cisplatin Uses, Side Effects & Warnings - Drugs.com

WebAug 6, 2024 · Cisplatin is a platinum-based chemotherapeutic agent that is widely used for the treatment of malignant tumors, such as cervical cancer, lung cancer, and ovarian cancer [3]. Cisplatin mainly induces cross-linking at the N7-position of guanosine, which modifies DNA to induce apoptosis and kill cancer cells [4]. WebCisplatin is a chemotherapy drug which is used to treat cancers including: sarcoma, small cell lung cancer, germ cell tumors, lymphoma, and ovarian cancer. While it is often …

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WebApr 13, 2024 · HIGHLIGHTS. who: Florentine S. B. Subtil et al. from the Department of Radiotherapy and Radiooncology, Philipps-University, Marburg, Germany have published the research: Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines, in the … WebJun 1, 2024 · IC90 of paclitaxel in HeLa Pac RB was increased from 69 pM, 440 pM, 2,561 pM and 10,337 pM on 0th, 1st, 2nd, 3rd and 4th months, respectively. Interestingly, the resistant cells were recovered to...

WebFeb 10, 2024 · Cisplatin is one of the most effective chemotherapy drugs and is widely used in the treatment of cancer, including hepatocellular carcinoma (HCC) and … WebA cisplatin-resistant cell subline, HeLa/CDDP cells, showed a 19-fold resistance to cisplatin compared with the parent cells. The subline showed a collateral sensitivity to paclitaxel. An equitoxic dose (IC50) of cisplatin produced DNA fragmentation in HeLa …

WebCisplatin, as a significant chemotherapeutic drug for the treatment of cancers, was combined with rapamycin (RAPA), an autophagy inducer, or 3-methyladenine (3-MA), an autophagy inhibitor, and these cisplatin … WebThe cis-Diammineplatinum (II) dichloride (cisplatin; P4394), 3- (4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT; M2128), and dimethyl sulfoxide (DMSO; D2650 for cell stock storage and D5979 for drug preparation) were purchased from Sigma (St. Louis, MO, USA).

WebApr 29, 2015 · Hypopharyngeal squamous cell carcinoma (HSCC) has the worst prognosis among head and neck cancers. Cisplatin (DDP)-based chemotherapy is an important part of multimodal treatments. However, resistance to DDP severely impairs the effectiveness of chemotherapy for HSCC.

WebAug 21, 2024 · Monitoring of the HeLa and HeLa-SypHer2 tumor growth during the 35 days after tumor challenge showed that cisplatin treatment (5 mg/kg, totaling 11 doses over 4 weeks) clearly impeded tumor growth. biofit uplift braWebFor IFNβ-cisplatin sequential treatment protocol (E), HeLa cells were treated with 100 ng/mL IFNβ for 24, 48, or 72 h, and then cells were replated in 96-well plates and treated … daikin air conditioner leaking waterWebNational Center for Biotechnology Information daikin air conditioner inverter priceWebAug 21, 2024 · Effect of cisplatin on the proliferative activity and survival of cancer cells. ( A) Viable cell number for HeLa and HeLa-SypHer2 cells. ( B) Percentage of dead (trypan blue positive) cells.... biofit vitamins contact infoWebNov 29, 2024 · Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment daikin air conditioner not coolingWebApr 21, 2024 · Cisplatin, as a significant chemotherapeutic drug for the treatment of cancers, was combined with rapamycin (RAPA), an autophagy inducer, or 3 … daikin air conditioner philippinesWebJul 1, 2009 · To test our hypothesis, we employed HeLa Tet (tetracycline)-off cells, which we previously used to overexpress the native plaa gene [21], and determined their apoptotic responses to cisplatin. HeLa cells were chosen because cervical tumor is a cisplatin-responsive tumor, while cervical tissues express the plaa gene [31], and respond to ... daikin air conditioner model numbers